{"id":191217,"date":"2021-10-25T17:00:00","date_gmt":"2021-10-25T09:00:00","guid":{"rendered":"https:\/\/heho.com.tw\/?p=191217"},"modified":"2021-10-25T15:18:31","modified_gmt":"2021-10-25T07:18:31","slug":"%e6%af%8f%e5%b9%b4%e8%8a%b1-132-%e5%84%84%e5%85%83%ef%bc%81%e7%b3%96%e5%b0%bf%e7%97%85%e5%8f%a3%e6%9c%8d%e9%99%8d%e8%a1%80%e7%b3%96%e8%97%a5%e6%9c%89%e5%93%aa%e4%ba%9b%ef%bc%9f%e5%b0%88%e5%ae%b6","status":"publish","type":"post","link":"https:\/\/heho.com.tw\/archives\/191217","title":{"rendered":"\u6bcf\u5e74\u82b1 132 \u5104\u5143\uff01\u7cd6\u5c3f\u75c5\u53e3\u670d\u964d\u8840\u7cd6\u85e5\u6709\u54ea\u4e9b\uff1f\u5c08\u5bb6\u8a73\u7d30\u5217\u8868\u4e00\u79d2\u8b80\u61c2"},"content":{"rendered":"\n

\u96a8\u8457\u570b\u4eba\u7cd6\u5c3f\u75c5\u767c\u751f\u7387\u9010\u5e74\u589e\u52a0\uff0c\u4e5f\u53cd\u6620\u65bc\u964d\u8840\u7cd6\u85e5\u7684\u5065\u4fdd\u7d66\u4ed8\u3002\u6839\u64da\u5065\u4fdd\u7f72\u6700\u65b0\u7d71\u8a08\u767c\u73fe\uff0c\u53bb\u5e74\u7528\u65bc\u6cbb\u7642\u7cd6\u5c3f\u75c5\u7684\u85e5\u7269\u7684\u8cbb\u7528\uff0c\u5c31\u82b1\u8cbb\u4e86\u7d04 132 \u5104\u5143\uff1b\u82e5\u52a0\u7e3d\u8a3a\u7642\u8cbb\u3001\u4f4f\u9662\u8cbb\u3001\u5176\u4ed6\u91ab\u6750\u7b49\u6cbb\u7642\u8cbb\u7528\uff0c\u7e3d\u652f\u51fa\u9ad8\u9054 267 \u5104\u5143\u3002<\/p>\n\n\n\n

\u7cd6\u5c3f\u75c5\u4e5f\u662f\u9020\u6210\u570b\u4eba\u6d17\u814e\u6700\u5927\u5143\u5147\uff0c\u800c\u814e\u81df\u75c5\u4e00\u76f4\u662f\u5065\u4fdd\u300c\u6700\u71d2\u9322\u300d\u75be\u75c5\uff0c\u64da 108 \u5e74\u7d71\u8a08\u767c\u73fe\uff0c\u6cbb\u7642\u8cbb\u7528\u5168\u5e74\u5ea6\u9ad8\u9054 533 \u5104\u5143\u3002\u82e5\u5c07\u7cd6\u5c3f\u75c5\u8207\u6162\u6027\u814e\u75c5\u7684\u5065\u4fdd\u652f\u51fa\u52a0\u7e3d\uff0c\u8cbb\u7528\u76f8\u7576\u53ef\u89c0\uff0c\u986f\u793a\u7cd6\u5c3f\u75c5\u9810\u9632\u8207\u6cbb\u7642\uff0c\u523b\u4e0d\u5bb9\u7de9\uff01<\/p>\n\n\n\n

\u7cd6\u5c3f\u75c5\u5feb\u6cbb\u7642\uff0c\u907f\u514d\u4f75\u767c\u75c7\u81f4\u547d<\/h2>\n\n\n\n

\u4e9e\u6771\u91ab\u9662\u65b0\u9673\u4ee3\u8b1d\u79d1\u4e3b\u6cbb\u91ab\u5e2b\u5085\u5fd7\u5ba3\u8868\u793a\uff0c\u5c0d\u65bc\u7b2c\u4e8c\u578b\u7cd6\u5c3f\u75c5<\/a>\uff0c\u82e5\u80fd\u53ca\u65e9\u767c\u73fe\u4e26\u6cbb\u7642\uff0c\u642d\u914d\u9069\u7576\u7684\u98f2\u98df\u8207\u904b\u52d5\u5c31\u80fd\u964d\u4f4e\u4f75\u767c\u75c7\u767c\u751f\uff1b\u5207\u52ff\u807d\u4fe1\u504f\u65b9\uff0c\u5ef6\u8aa4\u5c31\u91ab\u3002<\/p>\n\n\n\n

\u7cd6\u5c3f\u75c5\u7684\u6cbb\u7642\u4e26\u4e0d\u56f0\u96e3\uff0c\u53ef\u4f7f\u7528\u7684\u85e5\u7269\u7a2e\u985e\u975e\u5e38\u7684\u591a\uff0c\u80fd\u91dd\u5c0d\u60a3\u8005\u500b\u4eba\u7684\u751f\u7406\u72c0\u6cc1\u3001\u7528\u85e5\u9700\u6c42\u7b49\uff0c\u63d0\u4f9b\u6700\u9069\u7576\u7684\u8655\u65b9\u3002\u4ed6\u8aaa\uff1a\u300c\u7cd6\u53cb\u7121\u9808\u64d4\u5fc3\u6cbb\u7642\u6703\u5f71\u97ff\u751f\u6d3b\u54c1\u8cea\uff0c\u53cd\u800c\u662f\u53ca\u65e9\u4e14\u7a4d\u6975\u7684\u6cbb\u7642\uff0c\u624d\u80fd\u7dad\u6301\u7f8e\u597d\u7684\u751f\u6d3b\u3002\u300d<\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

\u7cd6\u5c3f\u75c5\u53e3\u670d\u85e5\u7a2e\u985e\u591a\uff0c\u5225\u64d4\u5fc3\u7121\u85e5\u53ef\u91ab<\/h2>\n\n\n\n

\u7cd6\u5c3f\u75c5\u662f\u56e0\u70ba\u9ad4\u5167\u80f0\u5cf6\u7d20\u7f3a\u4e4f\uff0c\u6216\u80f0\u5cf6\u7d20\u7121\u6cd5\u767c\u63ee\u6b63\u5e38\u529f\u80fd\uff0c\u4f7f\u8461\u8404\u7cd6\u4ee3\u8b1d\u5931\u5e38\uff0c\u9020\u6210\u8840\u6db2\u4e2d\u8840\u7cd6\u6fc3\u5ea6\u4e0a\u5347\u3002\u5085\u5fd7\u5ba3\u6307\u51fa\uff0c\u4f7f\u7528\u964d\u8840\u7cd6\u85e5\u7269\u9032\u884c\u6cbb\u7642\u6642\uff0c\u4e0d\u55ae\u53ea\u662f\u964d\u4f4e\u8840\u7cd6\u503c\uff0c\u66f4\u91cd\u8981\u7684\u662f\u5ef6\u7de9\u53ca\u9810\u9632\u76f8\u95dc\u4f75\u767c\u75c7\u767c\u751f\u3002<\/p>\n\n\n\n

\u4ed6\u63d0\u9192\uff0c\u7cd6\u5c3f\u75c5\u6cbb\u7642\u5df2\u9032\u5165\u300c\u53ca\u6642\u3001\u5168\u9762\u3001\u500b\u5225\u5316\u300d\uff0c\u85c9\u7531\u8a55\u4f30\u75c5\u4eba\u670d\u85e5\u9806\u5f9e\u6027\uff0c\u517c\u9867\u5fc3\u814e\u72c0\u614b\u3001\u5171\u75c5\u53ca\u4f75\u767c\u75c7\u7684\u8655\u7f6e\uff0c\u9032\u800c\u7d50\u5408\u4e0d\u540c\u4f5c\u7528\u6a5f\u8f49\u7684\u85e5\u7269\uff0c\u671f\u4ee5\u80fd\u5728\u77ed\u6642\u9593\u5167\u66ff\u60a3\u8005\u7a69\u5b9a\u63a7\u7cd6\uff0c\u8b93\u7cd6\u53cb\u5f97\u4ee5\u7dad\u6301\u5065\u5eb7\u751f\u6d3b\u3002<\/p>\n\n\n\n

\u76ee\u524d\uff0c\u9664\u4e86\u6ce8\u5c04\u80f0\u5cf6\u7d20\uff08Insulin\uff09\u4e4b\u5916\uff0c\u81e8\u5e8a\u4e0a\uff0c\u6700\u5e38\u4f7f\u7528\u7684\u53e3\u670d\u964d\u8840\u7cd6\u85e5\u7269\u53ef\u5206\u70ba\u4e03\u985e\uff0c\u5085\u5fd7\u5ba3\u89e3\u6790\u5176\u4f5c\u7528\u6a5f\u5236\u3001\u526f\u4f5c\u7528\u53ca\u6ce8\u610f\u4e8b\u9805\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Type 1 \u6e1b\u5c11\u8178\u9053\u8461\u8404\u7cd6\u7684\u5438\u6536\u8207\u809d\u81df\u7684\u8461\u8404\u7cd6\u65b0\u751f\u4f5c\u7528<\/h3>\n\n\n\n

\u6700\u5e38\u4f7f\u7528\u7684\u7b2c\u4e00\u7dda\u7528\u85e5 Metformin\uff08\u96d9\u80cd\u985e\u85e5\u7269\uff09\uff0c\u5373\u5c6c\u65bc\u6b64\u985e\u3002\u5b83\u80fd\u6e1b\u5c11\u8178\u9053\u5438\u6536\u8461\u8404\u7cd6\uff0c\u6e1b\u5c11\u809d\u81df\u7684\u8461\u8404\u7cd6\u65b0\u751f (gluconeogenesis)\uff0c\u4e26\u63d0\u5347\u80f0\u5cf6\u7d20\u7684\u654f\u611f\u6027\uff0c\u4f7f\u5f97\u8b93\u80f0\u5cf6\u7d20\u963b\u6297\u4e0b\u964d\uff0c\u4f7f\u5f97\u80f0\u5cf6\u7d20\u80fd\u767c\u63ee\u5176\u4f5c\u7528\u3002\u300c\u5927\u90e8\u5206\u7cd6\u53cb\uff0c\u9664\u975e\u6709\u7981\u5fcc\u75c7\uff0c\u57fa\u672c\u4e0a\u4e00\u5b9a\u6703\u4f7f\u7528\u7684\u53e3\u670d\u85e5\u5c31\u662f Metformin\u3002\u300d<\/p>\n\n\n\n

Type 2 \u4fc3\u9032\u80f0\u5cf6\u7d20\u7684\u5206\u6ccc\uff0c\u7531\u809d\u81df\u4ee3\u8b1d<\/h3>\n\n\n\n

\u80f0\u5cf6\u7d20\u662f\u8eab\u9ad4\u5167\u63a7\u5236\u8461\u8404\u7cd6\u4ee3\u8b1d\u5f88\u91cd\u8981\u7684\u8377\u723e\u8499\uff0c\u4fc3\u9032\u5176\u5206\u6ccc\u662f\u7cd6\u5c3f\u75c5\u6cbb\u7642\u7684\u65b9\u5f0f\u4e4b\u4e00\u3002\u78fa\u91af\u5c3f\u7d20\u985e\uff08Sulfonylurea\uff09\u53e3\u670d\u85e5\uff0c\u80fd\u8207\u80f0\u5cf6\u03b2\u7d30\u80de\u819c\u4e0a\u7684\u53d7\u9ad4\u7d50\u5408\uff0c\u523a\u6fc0\u80f0\u81df\u5206\u6ccc\u80f0\u5cf6\u7d20\uff0c\u4f86\u9054\u5230\u964d\u8840\u7cd6\u6548\u679c\u3002<\/p>\n\n\n\n

\u8a72\u985e\u85e5\u7269\u5927\u90e8\u5206\u90fd\u7d93\u7531\u809d\u81df\u4ee3\u8b1d\uff0c\u56e0\u6b64\u809d\u814e\u529f\u80fd\u4e0d\u4f73\u8005\uff0c\u4f7f\u7528\u6642\u8981\u7279\u5225\u6ce8\u610f\u3002\u6b64\u5916\uff0c\u4fc3\u9032\u80f0\u5cf6\u7d20\u5206\u6ccc\u4ee5\u8abf\u964d\u8840\u7cd6\u7684\u85e5\u7269\uff0c\u8f03\u5bb9\u6613\u7522\u751f\u4f4e\u8840\u7cd6\uff0c\u51fa\u73fe\u98e2\u9913\u611f\u3001\u7729\u6688\u3001\u5192\u51b7\u6c57\u3001\u986b\u6296\u3001\u982d\u75db<\/a>\u3001\u610f\u8b58\u6a21\u7cca\u3001\u9ad4\u91cd\u4e0a\u5347\u7b49\u526f\u4f5c\u7528\u3002<\/p>\n\n\n\n

Type 3 \u4fc3\u9032\u80f0\u5cf6\u7d20\u5206\u6ccc\uff0c\u9069\u5408\u814e\u529f\u80fd\u4e0d\u4f73<\/h3>\n\n\n\n

\u7f8e\u683c\u66ff\u8010\u985e\uff08Meglitinides\uff09\u85e5\u7269\uff0c\u8207\u78fa\u91af\u5c3f\u7d20\u985e\uff08Sulfonylurea\uff09\u7684\u4f5c\u7528\u985e\u4f3c\uff0c\u8207\u80f0\u5cf6\u03b2\u7d30\u80de\u819c 36kD \u7279\u7570\u86cb\u767d\u7d50\u5408\uff0c\u4f7f K+ \u901a\u9053\u95dc\u9589\u800c\u4fc3\u9032\u80f0\u5cf6\u7d20\u5206\u6ccc\uff0c\u800c\u964d\u4f4e\u8840\u7cd6\uff0c\u88ab\u7a31\u4f5c\u70ba\u975e\u78fa\u91af\u5c3f\u7d20\u985e\uff08Sulfonylurea\uff09\u4fc3\u80f0\u5cf6\u7d20\u5206\u6ccc\u53e3\u670d\u85e5\u3002Meglitinides \u985e\u85e5\u7269\u662f\u7531\u81bd\u9053\u6392\u9664\uff0c\u56e0\u6b64\uff0c\u9069\u7528\u65bc\u814e\u529f\u80fd\u4e0d\u826f\u8005\u3002\u8207\u78fa\u91af\u5c3f\u7d20\u985e\u85e5\u7269\u4e00\u6a23\u5bb9\u6613\u6709\u9ad4\u91cd\u4e0a\u5347\u3001\u4f4e\u8840\u7cd6\u7b49\u526f\u4f5c\u7528\u3002<\/p>\n\n\n\n

Type 4 \u6291\u5236\u5c0f\u8178\u7684\u8461\u8404\u7cd6\u82f7\u9176\uff0c\u5ef6\u7de9\u7cd6\u985e\u5438\u6536<\/h3>\n\n\n\n

\u4f5c\u7528\u65bc\u6d88\u5316\u9053\uff0c\u85c9\u7531\u6291\u5236\u6fb1\u7c89\u5206\u89e3\u6210\u8461\u8404\u7cd6\u53ca\u6e1b\u5c11\u5c0f\u8178\u5c0d\u8461\u8404\u7cd6\u7684\u5438\u6536\uff0c\u9054\u5230\u964d\u8840\u7cd6\u7684\u6548\u679c\uff0c\u7a31\u70ba\u300c\u03b1-\u8461\u8404\u7cd6\u82f7\u9176\u6291\u81f4\u5291\uff08\u03b1-Glucosidase Inhibitor\uff09\u300d\u3002\u5085\u5fd7\u5ba3\u8aaa\uff0c\u9019\u4e00\u985e\u7684\u85e5\u7269\u5c0d\u65bc\u9910\u5f8c\u8840\u7cd6\u503c\u7684\u4e0b\u964d\u662f\u6709\u5e6b\u52a9\u7684\uff0c\u5982\u7cd6\u53cb\u9910\u5f8c\u8840\u7cd6\u6bd4\u8f03\u9ad8\uff0c\u5c31\u53ef\u80fd\u6703\u8003\u616e\u9078\u64c7\u6b64\u985e\u85e5\u7269\u3002<\/p>\n\n\n\n

Type 5 \u80f0\u5cf6\u7d20\u589e\u654f\u5291\uff0c\u589e\u52a0\u80f0\u5cf6\u7d20\u7684\u654f\u611f\u6027<\/h3>\n\n\n\n

Thiazolidinediones\uff08TZD\uff09\uff0c\u5b83\u85c9\u7531\u80fd\u6d3b\u5316 PPAR-\u03b3\uff08\u80f0\u5cf6\u7d20\u589e\u654f\u5291\u53d7\u9ad4\uff09\u7684\u4f5c\u7528\uff0c\u9054\u5230\u589e\u52a0\u80f0\u5cf6\u7d20\u7684\u654f\u611f\u6027\uff0c\u964d\u4f4e\u80f0\u5cf6\u7d20\u7684\u963b\u6297\u6027\uff0c\u589e\u52a0\u8102\u80aa\u7d30\u80de\u5438\u6536\u6e38\u96e2\u8102\u80aa\u9178\u53ca\u9aa8\u9abc\u808c\u651d\u53d6\u8461\u8404\u7cd6\u6548\u7387\uff0c\u9054\u5230\u63a7\u5236\u8840\u7cd6\u7684\u6548\u679c\u3002<\/p>\n\n\n\n

Type 6 \u589e\u52a0\u8178\u6ccc\u7d20\u6fc3\u5ea6\uff0c\u6e1b\u6162\u8461\u8404\u7cd6\u5438\u6536<\/h3>\n\n\n\n

DPP-4 \u6291\u5236\u5291\uff08DPP-4 Inhibitor\uff09\uff0c\u53ef\u4fc3\u9032\u9ad4\u5167\u8178\u6ccc\u7d20\u6fc3\u5ea6\u589e\u52a0\uff0c\u4f7f\u03b2\u7d30\u80de\u88fd\u9020\u5206\u6ccc\u80f0\u5cf6\u7d20\uff0c\u4e26\u6291\u5236\u80f0\u81df\u03b1\u7d30\u80de\u5206\u6ccc\u5347\u7cd6\u7d20\uff0c\u4ee5\u964d\u4f4e\u809d\u91a3\u751f\u6210\u4f5c\u7528\uff0c\u5ef6\u7de9\u80c3\u6392\u7a7a\u7684\u901f\u7387\uff0c\u6e1b\u6162\u8461\u8404\u7cd6\u4e4b\u5438\u6536\u3002\u9069\u5408\u9910\u5f8c\u8840\u7cd6\u503c\u8f03\u9ad8\u7684\u7cd6\u53cb\u4f7f\u7528\u3002<\/p>\n\n\n\n

Type 7 \u5c07\u5c3f\u7cd6\u6392\u51fa\u9ad4\u5916\uff0c\u5f97\u4ee5\u964d\u4f4e\u8840\u7cd6<\/h3>\n\n\n\n

\u6291\u5236\u9209-\u8461\u8404\u7cd6\u8f49\u904b\u86cb\u767d\u6291\u5236\u5291\uff08SGLT-2 Inhibitor\uff09\uff0c\u80fd\u6291\u5236\u814e\u5c0f\u7ba1\u628a\u8840\u7cd6\u518d\u5438\u6536\u4f5c\u7528\uff0c\u4f7f\u5927\u90e8\u5206\u7684\u8840\u7cd6\u96a8\u5c3f\u6db2\u6392\u51fa\u9ad4\u5916\uff0c\u800c\u9054\u5230\u964d\u4f4e\u8840\u7cd6\u4e4b\u6548\u3002\u7814\u7a76\u767c\u73fe\uff0c\u9084\u80fd\u964d\u4f4e\u5fc3\u814e\u75c5\u8b8a\u7684\u98a8\u96aa\uff0c\u6210\u70ba\u73fe\u4eca\u85e5\u7269\u6cbb\u7642\u7684\u4e3b\u6d41\u85e5\u7269\u4e4b\u4e00\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u6587 \/ \u9ec3\u6167\u73ab\u3001\u5716 \/ \u4f55\u5b9c\u5ead<\/p>\n\n\n\n

\u5ef6\u4f38\u95b1\u8b80\uff1a<\/strong>
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